Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144658 | 0.93 | CYP3A4 (0.50) | ENPP2ATXN2ACACBHSD17B10MEN1 | |
| SCHEMBL14249585 | 0.93 | ENPP2 (0.56) | ENPP2ATXN2ACACBMEN1KMT2A | |
| SCHEMBL13805600 | 0.93 | MEN1 (0.54) | ENPP2ATXN2ACACBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28384503 | 0.92 | CYP3A4 (0.49) | ENPP2ATXN2ACACBHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL14249583 | 0.91 | ENPP2 (0.55) | ENPP2ATXN2ACACBMEN1KMT2A | |
| SCHEMBL30741614 | 0.91 | ENPP2 (0.49) | ENPP2ATXN2ACACBHSD17B10MEN1 | |
| SCHEMBL614422 | 0.91 | ENPP2 (0.57) | ENPP2ATXN2ACACBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28379028 | 0.90 | ATXN2 (0.56) | ENPP2ATXN2ACACBMEN1KMT2A | |
| SCHEMBL30484110 | 0.87 | MEN1 (0.57) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL30121235 | 0.86 | MEN1 (0.56) | ENPP2ATXN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218597-A1 | SUBSTITUTED PYRIDINES AND METHODS OF USE | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-07-13 | — | — | US | disclosed |
| WO-2019029620-A1 | ATX INHIBITORS, PREPARATION METHOD THEREFOR AND APPLICATIONS THEREOF | 广州市恒诺康医药科技有限公司 | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218597-A1 | SUBSTITUTED PYRIDINES AND METHODS OF USE | ALK, ACVR1, ACVR2A | ENPP2 67/4885ATXN2 3736/4885ACACB 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.