Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.49 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.49 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.49 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708978 | 0.91 | KMT2A (0.48) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL26090058 | 0.89 | POLM (0.62) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL20739827 | 0.89 | POLM (0.62) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL4085609 | 0.85 | MEN1 (0.67) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL29081006 | 0.84 | KMT2A (0.49) | MEN1KMT2AKDM4ERECQLMAPT | |
| SCHEMBL4090350 | 0.83 | MEN1 (0.60) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL5701570 | 0.83 | KMT2A (0.56) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL28936425 | 0.83 | KMT2A (0.56) | MEN1KMT2AKDM4ERECQLMAPT | |
| SCHEMBL30666136 | 0.82 | POLM (0.67) | MEN1KMT2APPARGKDM4ERECQL | |
| SCHEMBL4083649 | 0.82 | MEN1 (0.59) | MEN1KMT2APPARGKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288279-B1 | 1,3-DIOXANES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-09-09 | — | — | EP | disclosed |
| EP-0304138-B1 | PROCESS FOR MAKING 1,3-DIOXANE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-04 | — | — | EP | disclosed |
| EP-0304139-B1 | PROCESS FOR MAKING 5-HYDROXY-3-HYDROXYMETHYL-2-PHENYLFURAN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |
| EP-0304139-A1 | Process for making 5-hydroxy-3-hydroxymethyl-2-phenylfuran derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0304138-A1 | Process for making 1,3-dioxane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0266979-A2 | Therapeutic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |