Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 2/20 | 0.59 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.57 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.57 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.57 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22975372 | 1.00 | MEN1 (0.59) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL4083842 | 1.00 | MEN1 (0.59) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL9186714 | 1.00 | MEN1 (0.59) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL4089868 | 1.00 | MEN1 (0.59) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL4090350 | 0.98 | MEN1 (0.60) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL4085609 | 0.93 | MEN1 (0.67) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL10571781 | 0.93 | KMT2A (0.66) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL15549264 | 0.93 | KMT2A (0.66) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL15548290 | 0.93 | KMT2A (0.66) | MEN1KMT2AKDM4ERECQLTOP2A | |
| SCHEMBL15546549 | 0.93 | KMT2A (0.66) | MEN1KMT2AKDM4ERECQLTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237683-B1 | METHOD OF FLAVORING | GIVAUDAN SA (CH) | 2015-11-11 | — | — | EP | disclosed |
| EP-2237683-B1 | METHOD OF FLAVORING | GIVAUDAN SA (CH) | 2015-11-11 | — | — | EP | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20130177688-A1 | Method of Flavoring | GIVAUDAN S.A. (CH) | 2013-07-11 | — | — | US | disclosed |
| WO-2009092176-A2 | METHOD OF FLAVORING | GIVAUDAN SA (CH) | 2009-07-30 | — | — | WO | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
| US-20090186138-A1 | Method of Flavoring | GIVAUDAN SA (CH) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186138-A1 | Method of Flavoring | TAS2R5, TAS2R50, TAS2R10 | MEN1 3519/4885KMT2A 1234/4885KDM4E 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.