SCHEMBL20739845

SCHEMBL20739845

Cc1c(C#N)cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
KDM4E B2RXH2 6/20 0.49
HPGD P15428 4/20 0.49
GAA P10253 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
GALR3 O60755 1/20 0.49
GLA P06280 1/20 0.46
PTGS1 P23219 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
MCL1 Q07820 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
HSD17B10 Q99714 1/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
XDH P47989 1/20 0.41
TSHR P16473 1/20 0.41
GRM6 O15303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20739844 0.88 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL16581274 0.81 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL27832590 0.80 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL20663065 0.80 PTGS1 (0.58) ALDH1A1KDM4EHPGDNPSR1PTGS1
SCHEMBL20751800 0.78 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL4506623 0.77 NISCH (0.49) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL24017160 0.75 METAP2 (0.50) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL8665465 0.75 MCL1 (0.51) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL22420407 0.75 CYP11B1 (0.51) ALDH1A1KDM4EHPGDGAANPSR1
SCHEMBL12679759 0.74 ADORA1 (0.55) ALDH1A1KDM4EHPGDGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190051832-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-02-14 US disclosed