⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20740317 | 1.00 | — | — | |
| SCHEMBL1830663 | 0.70 | L3MBTL1 (0.32) | — | |
| SCHEMBL1604058 | 0.70 | L3MBTL1 (0.32) | — | |
| Water SCHEMBL1831822 | 0.69 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29571133 | 0.69 | L3MBTL1 (0.31) | — | |
| Lx-2931 SCHEMBL304963 | 0.65 | L3MBTL1 (0.33) | — | |
| Lx-2931 SCHEMBL20744226 | 0.65 | L3MBTL1 (0.33) | — | |
| Lx-2931 SCHEMBL20744228 | 0.65 | L3MBTL1 (0.33) | — | |
| Lx-2931 SCHEMBL316870 | 0.65 | L3MBTL1 (0.33) | — | |
| Lx-2931 SCHEMBL304964 | 0.65 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850234-B2 | Enhancement of cancer treatment efficiency via the sphingosine-1-phosphate pathway | AC BIOSCIENCE (CH) | 2023-12-26 | — | — | US | disclosed |
| US-20200261420-A1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | AC BIOSCIENCE (CH) | 2020-08-20 | — | — | US | disclosed |
| EP-3668506-A1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | AC BioScience (CH) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034768-A1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | AC BIOSCIENCE (CH) | 2019-02-21 | — | — | WO | disclosed |
| EP-3443986-A1 | ENHANCEMENT OF CHEMOTHERAPY EFFICIENCY BY SPHINGOSINE-1-PHOSPHATE | AC BioScience (CH) | 2019-02-20 | — | — | EP | disclosed |