Lx-2931

Lx-2931

SCHEMBL304963

C/C(=N\O)c1nc([C@@H](O)[C@H](O)[C@H](O)CO)c[nH]1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lx-2931 SCHEMBL20744228 1.00 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL304964 1.00 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL20744226 1.00 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL316870 1.00 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL306099 0.99 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL306100 0.99 L3MBTL1 (0.33) L3MBTL1CYP1A2
Lx-2931 SCHEMBL4382659 0.99 L3MBTL1 (0.33) L3MBTL1CYP1A2
SCHEMBL316038 0.87 L3MBTL1 (0.30) L3MBTL1
SCHEMBL10069449 0.87 L3MBTL1 (0.30) L3MBTL1
SCHEMBL316037 0.87 L3MBTL1 (0.30) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027051-A1 SPHINGOSINE-1-PHOSPHATE LYASE INHIBITORS FOR USE IN THE TREAMENT OF NEURODEGENERATIVE DISEASES AB SCIENCE (FR) 2025-02-06 WO claimed
US-20170304326-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE CLIO, INC. (JP) 2017-10-26 US claimed
US-20160354393-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE TOHOKU UNIVERSITY (JP) 2016-12-08 US claimed
US-20160008340-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO INJURY TOHOKU UNIVERSITY (JP) 2016-01-14 US claimed
EP-2962698-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO INJURY Clio, Inc. (JP) 2016-01-06 EP claimed
EP-2139864-B1 METHODS OF PREPARING 1-(4-(1-HYDROXYALKYL)-1H-IMIDAZOL-2-YL)ETHANONE OXIME COMPOUNDS LEXICON PHARMACEUTICALS INC (US) 2015-12-02 EP claimed
US-20140051729-A1 COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE MUSCLE CONDITIONS UNIVERSITY OF WASHINGTON (US) 2014-02-20 US claimed
US-8404732-B2 Methods of treating ulcerative colitis LEXICON PHARMACEUTICALS, INC. (US) 2013-03-26 US claimed
US-20130005775-A1 METHODS OF TREATING ULCERATIVE COLITIS LEXICON PHARMACEUTICALS, INC. (US) 2013-01-03 US claimed
WO-2012097330-A2 COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE MUSCLE CONDITIONS UNIVERSITY OF WASHINGTON (US) 2012-07-19 WO claimed
US-7825150-B2 Compositions and methods for treating immunological and inflammatory diseases and disorders LEXICON PHARMACEUTICALS, INC. (US) 2010-11-02 US claimed
US-7812174-B2 Methods of preparing imidazole-based compounds LEXICON PHARMACEUTICALS, INC. (US) 2010-10-12 US claimed
US-20100113530-A1 S1P LYASE INHIBITORS FOR THE TREATMENT OF CEREBRAL MALARIA LEXICON PHARMACEUTICALS, INC. 2010-05-06 US claimed
US-20100076030-A1 METHODS OF TREATING RHEUMATOID ARTHRITIS LEXICON PHARMACEUTICALS, INC. (US) 2010-03-25 US claimed
US-7649098-B2 Imidazole-based compounds, compositions comprising them and methods of their use LEXICON PHARMACEUTICALS, INC. (US) 2010-01-19 US claimed
EP-2090334-A2 Imidazole based compounds, compositions comprising them and methods of their use Lexicon Pharmaceuticals, Inc. (US) 2009-08-19 EP claimed
US-20090068180-A1 COMPOSITIONS AND METHODS FOR TREATING IMMUNOLOGICAL AND INFLAMMATORY DISEASES AND DISORDERS OXFORD FINANCE LLC, AS COLLATERAL AGENT 2009-03-12 US claimed
US-20080275099-A1 Solid Forms of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime LEXICON PHARMACEUTICALS, INC. 2008-11-06 US claimed
US-20080262241-A1 Methods of Preparing Imidazole-Based Compounds OXFORD FINANCE LLC, AS COLLATERAL AGENT 2008-10-23 US claimed
US-20070208063-A1 Imidazole-based compounds, compositions comprising them and methods of their use OXFORD FINANCE LLC, AS COLLATERAL AGENT 2007-09-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113530-A1 S1P LYASE INHIBITORS FOR THE TREATMENT OF CEREBRAL MALARIA S1PR1, S1PR2, SPHK1 L3MBTL1 1382/4885CYP1A2 2113/4885
US-20090068180-A1 COMPOSITIONS AND METHODS FOR TREATING IMMUNOLOGICAL AND INFLAMMATORY DISEASES AND DISORDERS ASAH2, SGMS1, SMPD1 L3MBTL1 3610/4885CYP1A2 2181/4885
US-20140051729-A1 COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE MUSCLE CONDITIONS CPT1B, S1PR1, PYGM L3MBTL1 2590/4885CYP1A2 4740/4885
US-20160008340-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO INJURY S1PR1, S1PR3, S1PR4 L3MBTL1 3911/4885CYP1A2 4436/4885
US-20170304326-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE S1PR1, S1PR3, S1PR4 L3MBTL1 4108/4885CYP1A2 4463/4885
US-20070208063-A1 Imidazole-based compounds, compositions comprising them and methods of their use TPMT, INMT, NFKBIA L3MBTL1 4383/4885CYP1A2 332/4885
US-20080262241-A1 Methods of Preparing Imidazole-Based Compounds PAICS, TOP2B, PPIP5K2 L3MBTL1 4548/4885CYP1A2 82/4885
US-20080275099-A1 Solid Forms of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime CYP2E1, OPRK1, SULT1E1 L3MBTL1 3001/4885CYP1A2 20/4885
US-20160354393-A1 PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO DAMAGE S1PR1, S1PR3, S1PR4 L3MBTL1 4108/4885CYP1A2 4463/4885
US-20100076030-A1 METHODS OF TREATING RHEUMATOID ARTHRITIS SSB, NFKBIA, MPO L3MBTL1 4705/4885CYP1A2 1019/4885
US-20130005775-A1 METHODS OF TREATING ULCERATIVE COLITIS SI, S1PR2, SPHK2 L3MBTL1 3844/4885CYP1A2 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.