Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.52 |
| ▸ | MMP8 | P22894 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | FCER2 | P06734 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20740927 | 1.00 | MME (0.55) | MMEMMP1MMP2MMP3KMT2A | |
| SCHEMBL19547920 | 0.90 | REN (0.49) | MMEMMP1MMP2MMP3REN | |
| SCHEMBL19547922 | 0.90 | REN (0.49) | MMEMMP1MMP2MMP3REN | |
| SCHEMBL19547913 | 0.88 | CTSL (0.58) | MMEMMP1MMP2MMP3REN | |
| SCHEMBL16571295 | 0.88 | CTSL (0.58) | MMEMMP1MMP2MMP3REN | |
| SCHEMBL19547923 | 0.87 | REN (0.48) | MMEMMP1MMP2MMP3KMT2A | |
| SCHEMBL19547924 | 0.87 | REN (0.48) | MMEMMP1MMP2MMP3KMT2A | |
| SCHEMBL16571387 | 0.87 | REN (0.48) | MMEMMP1MMP2MMP3KMT2A | |
| SCHEMBL19762064 | 0.87 | KMT2A (0.55) | MMEMMP1MMP2MMP3KMT2A | |
| SCHEMBL19547930 | 0.85 | REN (0.52) | MMEMMP1MMP2MMP3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055283-A1 | AZA-PEPTIDE ALDEHYDES AND KETONES | OHIO STATE INNOVATION FOUNDATION | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055283-A1 | AZA-PEPTIDE ALDEHYDES AND KETONES | VIP, DNPEP, PEPD | MME 73/4885MMP1 55/4885MMP2 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.