Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992002 | 0.98 | CHRNA7 (0.37) | TSHRCHRNA7HTR2AL3MBTL1MBTD1 | |
| SCHEMBL3714891 | 0.80 | KDM4E (0.34) | CHRNA7HTR2AHTR6ALDH1A1KDM4E | |
| SCHEMBL14011022 | 0.78 | TSHR (0.38) | TSHRCYP2D6L3MBTL1L3MBTL3P2RX1 | |
| SCHEMBL4858135 | 0.78 | TSHR (0.38) | TSHRCYP2D6L3MBTL1L3MBTL3P2RX1 | |
| SCHEMBL4858132 | 0.78 | TSHR (0.38) | TSHRCYP2D6L3MBTL1L3MBTL3P2RX1 | |
| SCHEMBL4855756 | 0.75 | TSHR (0.36) | TSHRCHRNA7CYP2D6L3MBTL1MBTD1 | |
| SCHEMBL4855750 | 0.75 | TSHR (0.36) | TSHRCHRNA7CYP2D6L3MBTL1MBTD1 | |
| SCHEMBL14011232 | 0.75 | TSHR (0.36) | TSHRCHRNA7CYP2D6L3MBTL1MBTD1 | |
| SCHEMBL2519261 | 0.74 | TSHR (0.44) | TSHRCYP2D6CYP2C19ALDH1A1USP2 | |
| SCHEMBL11798735 | 0.72 | HTR6 (0.44) | CHRNA7HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164913-A | Indenopiperidine derivatives, and preparation method and application thereof | 浙江大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118164913-A | Indenopiperidine derivatives, and preparation method and application thereof | 浙江大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-118164913-A | Indenopiperidine derivatives, and preparation method and application thereof | 浙江大学 | 2024-06-11 | — | — | CN | disclosed |
| US-7863294-B2 | Heterocycle derivatives as histone deacetylase (HDAC) inhibitors | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-01-04 | — | — | US | disclosed |
| CN-1091288-A | The oxytocin antagonist | OTSUKA PHARMA CO LTD (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0110521-B1 | PHENYLINDENE DERIVATIVES, ACID ADDITION SALTS THEREOF, AND METHODS OF PREPARATION | KEFALAS A/S (DK) | 1988-10-12 | — | — | EP | disclosed |
| US-4525360-A | Anti-psychotic phenylindene derivatives and acid addition salts thereof | KEFALAS A/S (DK) | 1985-06-25 | — | — | US | disclosed |
| EP-0110521-A2 | Phenylindene derivatives, acid addition salts thereof, and methods of preparation | KEFALAS A/S (DK) | 1984-06-13 | — | — | EP | disclosed |