Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA9 | Q16790 | 9/20 | 0.40 |
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20757925 | 0.79 | CA12 (0.43) | CA12CA1CA9CA2CA7 | |
| SCHEMBL23328665 | 0.77 | CA12 (0.41) | CA12CA1CA9CA2CA7 | |
| SCHEMBL20743272 | 0.74 | CA12 (0.39) | CA12CA1CA9CA2CA7 | |
| SCHEMBL20743212 | 0.73 | SMN1; SMN2 (0.41) | CA12CA1CA9CA2CHRNA7 | |
| SCHEMBL30812958 | 0.63 | GNE (0.60) | CA12CA1CA9CA2CA7 | |
| SCHEMBL22019981 | 0.62 | CA2 (0.36) | CA12CA1CA9CA2CA7 | |
| SCHEMBL20757369 | 0.60 | TMEM97 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL28873759 | 0.60 | ALDH1A1 (0.51) | CA12CA1CA9CA2CA7 | |
| SCHEMBL14912522 | 0.60 | KDM4E (0.46) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL22656980 | 0.59 | KDM4E (0.50) | CA12CA1CA9CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668862-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | Inflazome Limited (IE) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034688-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |