Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093693 | 0.77 | RAPGEF4 (0.42) | TSHRRAPGEF4ALDH1A1 | |
| SCHEMBL57436 | 0.77 | MEN1 (0.53) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7533055 | 0.75 | S1PR2 (0.50) | — | |
| SCHEMBL8829718 | 0.74 | TSHR (0.42) | TSHRRAPGEF4ALDH1A1MAPTMEN1 | |
| SCHEMBL1486303 | 0.74 | NPC1 (0.43) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10466069 | 0.73 | HSD17B10 (0.44) | TSHRALDH1A1MAPTGAAALOX12 | |
| SCHEMBL2097674 | 0.72 | ALDH1A1 (0.39) | TSHRRAPGEF4ALDH1A1MAPTMEN1 | |
| SCHEMBL424460 | 0.70 | RAPGEF4 (0.42) | TSHRRAPGEF4ALDH1A1MAPTMEN1 | |
| SCHEMBL7497080 | 0.69 | MEN1 (0.52) | TSHRRAPGEF4ALDH1A1MAPTMEN1 | |
| SCHEMBL2095962 | 0.69 | EPHX1 (0.52) | RAPGEF4ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929695-A | Sulfenimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2022-01-14 | — | — | CN | claimed |
| CN-102633892-B | Polysaccharide derivates and the agent for separating optical isomers containing this polysaccharide derivates | DAICEL CHEMICAL INDUSTRIES CO., LTD. (JP) | 2016-02-24 | — | — | CN | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| CN-113929695-B | Sulfimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-113929695-A | Sulfenimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2022-01-14 | — | — | CN | disclosed |
| US-20180056270-A1 | AMYLOSE DERIVATIVE AND OPTICAL ISOMER SEPARATING AGENT CONTAINING SAME | DAICEL CORPORATION (JP) | 2018-03-01 | — | — | US | disclosed |
| EP-3071560-B1 | N-ACYLIMINO HETEROCYCLIC COMPOUNDS | BASF SE (DE) | 2018-01-10 | — | — | EP | disclosed |
| CN-107245055-A | The preparation method of iprodione | 江苏蓝丰生物化工股份有限公司 | 2017-10-13 | — | — | CN | disclosed |
| US-9783523-B2 | N-acylimino heterocyclic compounds | BASF SE (DE) | 2017-10-10 | — | — | US | disclosed |
| EP-2592095-B1 | POLYSACCHARIDE DERIVATIVE, METHOD FOR PRODUCING THE SAME, AND SEPARATING AGENT | DAICEL CORP (JP) | 2017-05-24 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |