Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737394 | 1.00 | ESR2 (0.41) | ESR2HRH3GAAMAPK1MAPT | |
| SCHEMBL8448364 | 0.94 | ESR2 (0.43) | ESR2HRH3GAAMAPK1MAPT | |
| SCHEMBL8448366 | 0.94 | ESR2 (0.43) | ESR2HRH3GAAMAPK1MAPT | |
| SCHEMBL10932075 | 0.92 | ESR2 (0.46) | ESR2GAAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL2976250 | 0.91 | ESR2 (0.43) | ESR2HRH3DRD2DRD3CHRM2 | |
| SCHEMBL10927661 | 0.90 | ESR2 (0.42) | ESR2GAAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10929275 | 0.90 | ESR2 (0.42) | ESR2GAAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10932655 | 0.90 | ESR2 (0.42) | ESR2GAAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10931202 | 0.89 | ESR2 (0.44) | ESR2HRH3GAAMAPK1DRD2 | |
| SCHEMBL20744656 | 0.89 | ESR2 (0.47) | ESR2GAAMAPK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846670-A1 | CYCLOHEXANE DERIVATIVES AND LIQUID-CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1998-06-10 | — | — | EP | disclosed |