Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448364 | 1.00 | ESR2 (0.43) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10932075 | 0.95 | ESR2 (0.46) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8737394 | 0.94 | ESR2 (0.41) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8737396 | 0.94 | ESR2 (0.41) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10931056 | 0.92 | ESR2 (0.47) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL20744656 | 0.92 | ESR2 (0.47) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11190434 | 0.87 | ESR2 (0.54) | ESR2GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28008442 | 0.86 | ESR2 (0.45) | ESR2MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL10931202 | 0.86 | ESR2 (0.44) | ESR2GAAMAPK1DRD2DRD3 | |
| SCHEMBL11195824 | 0.85 | ESR2 (0.53) | ESR2RAB9ANPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |