Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20691038 | 0.82 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL22212156 | 0.80 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL20691037 | 0.72 | ALDH1A1 (0.42) | MEN1KMT2A | |
| SCHEMBL21889149 | 0.72 | KMT2A (0.41) | MEN1KMT2A | |
| SCHEMBL12693226 | 0.67 | PDE2A (0.32) | MEN1KMT2A | |
| SCHEMBL20690994 | 0.67 | L3MBTL1 (0.35) | MEN1KMT2A | |
| SCHEMBL20710036 | 0.64 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL21217940 | 0.64 | SMN1; SMN2 (0.39) | MEN1KMT2A | |
| SCHEMBL19214734 | 0.59 | — | — | |
| SCHEMBL20691025 | 0.59 | NAMPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208032-B2 | Benzamide and nicotinamide compounds and methods of using same | ONCOTARTIS INC. (US) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208032-B2 | Benzamide and nicotinamide compounds and methods of using same | NAMPT, NNT, NADK | MEN1 976/4885KMT2A 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.