Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20747681 | 1.00 | LMNA (0.52) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL12120676 | 0.98 | LMNA (0.48) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL10087909 | 0.92 | LMNA (0.46) | LMNACYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL10087766 | 0.86 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL10087760 | 0.86 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL10087759 | 0.86 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL10087764 | 0.86 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL10087765 | 0.86 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL27780045 | 0.85 | LMNA (0.52) | LMNAMAPTMEN1KMT2AATM | |
| SCHEMBL10087895 | 0.84 | ELANE (0.43) | LMNACYP4F2CYP4A11MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | LMNA 2972/4885CYP4F2 950/4885CYP4A11 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.