Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614334 | 0.76 | NFKB1 (0.44) | BRD4MIFHDAC6GAAKMT2A | |
| SCHEMBL13740156 | 0.67 | BRD4 (0.34) | BRD4MIFHDAC6GAAKMT2A | |
| SCHEMBL20809859 | 0.66 | BRD4 (0.33) | BRD4MIFHDAC6GAAKMT2A | |
| SCHEMBL16287303 | 0.65 | — | — | |
| SCHEMBL12848161 | 0.64 | TSHR (0.33) | BRD4MIFHDAC6GAAKMT2A | |
| SCHEMBL16614390 | 0.61 | TSHR (0.34) | BRD4MIFHDAC6GAA | |
| SCHEMBL1691605 | 0.61 | USP2 (0.46) | BRD4MIFHDAC6GAA | |
| SCHEMBL13359529 | 0.61 | USP2 (0.46) | BRD4MIFHDAC6GAA | |
| SCHEMBL18194690 | 0.61 | TSHR (0.34) | BRD4MIFHDAC6GAA | |
| SCHEMBL18194648 | 0.61 | TSHR (0.34) | BRD4MIFHDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928869-B1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |