Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.45 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 5/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691605 | 1.00 | USP2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL16614310 | 1.00 | USP2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10837418 | 0.89 | USP2 (0.38) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL7195271 | 0.87 | USP2 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10315910 | 0.81 | ALDH1A1 (0.63) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL14065524 | 0.80 | ALDH1A1 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL4428008 | 0.80 | USP2 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL28857857 | 0.79 | TDP1 (0.42) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL19259374 | 0.79 | ALDH1A1 (0.49) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL12987236 | 0.78 | USP2 (0.44) | USP2ALDH1A1ALOX15TDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186795-A1 | (1S, 2S, 3S, 4R)-3-Ý(1S)-1-ACETYLAMINO-2-ETHYL-BUTYL¨-4-GUANIDINO-2- HYDROXYL-CYCLOPENTYL-1-CARBOXYLIC ACID HYDRATES AND PHARMACEUTICAL USES THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2010-05-19 | — | — | EP | disclosed |
| US-20070112030-A1 | Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto | MERCK & CO., INC. | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112030-A1 | Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto | GRM1, GRM3, GRM2 | USP2 3996/4885ALDH1A1 2992/4885ALOX15 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.