Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20748761 | 0.82 | CTSK (0.38) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL19432382 | 0.78 | CTSK (0.36) | CTSKCA2CA1CA7NFKB1 | |
| SCHEMBL5409226 | 0.76 | CTSK (0.45) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL5409221 | 0.76 | CTSK (0.45) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL20686893 | 0.74 | CTSK (0.33) | CTSKCA2CA1CA7 | |
| SCHEMBL19193058 | 0.73 | CTSK (0.39) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL25793732 | 0.71 | DGAT1 (0.35) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL18786582 | 0.71 | CTSK (0.37) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL101218 | 0.70 | DGAT1 (0.46) | CTSKCA2DGAT1CA1CA7 | |
| SCHEMBL3509747 | 0.68 | DGAT1 (0.46) | CTSKCA2DGAT1CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134124-B1 | IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-02-20 | — | — | EP | disclosed |