Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | CTSE | P14091 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21444709 | 0.98 | CYP3A4 (0.39) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL21103427 | 0.96 | REN (0.40) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL20902069 | 0.94 | CYP3A4 (0.39) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL21699517 | 0.94 | SSTR2 (0.37) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL21699526 | 0.94 | CYP3A4 (0.39) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL21699557 | 0.92 | SSTR2 (0.38) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL19841574 | 0.92 | CYP3A4 (0.37) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL15811693 | 0.92 | CYP3A4 (0.37) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL22419930 | 0.92 | CYP3A4 (0.37) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL18602020 | 0.92 | CYP3A4 (0.37) | SSTR2CYP3A4CTSDCTSEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-3607996-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3498301-A1 | KIT COMPRISING IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2019-06-19 | — | — | EP | disclosed |
| EP-3134124-B1 | IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-02-20 | — | — | EP | disclosed |