SCHEMBL20749174

SCHEMBL20749174

OCC1CCC1c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19262111 0.82 HTR2C (0.63) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL16585369 0.82 HTR2C (0.63) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL16585368 0.82 HTR2C (0.63) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL13591154 0.82 HTR2C (0.63) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL7850670 0.79 HTR2A (0.40) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL7850673 0.79 HTR3A (0.53) SLC6A3
SCHEMBL3833873 0.77 SLC6A3 (0.72) SLC6A3
SCHEMBL7812342 0.77 SLC6A3 (0.72) SLC6A3
SCHEMBL7812339 0.77 SLC6A3 (0.72) SLC6A3
SCHEMBL3832789 0.77 SLC6A3 (0.72) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443959-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN Bio-Pharm Solutions Co., Ltd. (KR) 2019-02-20 EP disclosed