SCHEMBL20749294

SCHEMBL20749294

O=C/C=C/c1sc(Cl)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
PSMD14 O00487 1/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL859722 0.77
SCHEMBL20604374 0.73 PDK2 (0.31)
SCHEMBL20604371 0.73 PDK2 (0.31)
SCHEMBL25428148 0.71 TSHR (0.37) KMT2ALMNAALDH1A1HPGDTSHR
SCHEMBL2517642 0.67
SCHEMBL24664333 0.65 ALDH1A1 (0.33) ALDH1A1
SCHEMBL16808669 0.63 CA12 (0.43) MAPTLMNAALDH1A1
SCHEMBL4743016 0.62 KDM4E (0.33)
SCHEMBL4743015 0.62 KDM4E (0.33)
SCHEMBL15751858 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443959-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN Bio-Pharm Solutions Co., Ltd. (KR) 2019-02-20 EP disclosed