SCHEMBL859722

SCHEMBL859722

O=Cc1sc(Cl)nc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL909604 0.78
SCHEMBL2517642 0.78
SCHEMBL20749294 0.77 MEN1 (0.32)
Ethylene SCHEMBL3310698 0.76 LMNA (0.36)
SCHEMBL13451549 0.73 MEN1 (0.35)
SCHEMBL14495988 0.73 KMT2A (0.57)
SCHEMBL17385370 0.73 MEN1 (0.41)
SCHEMBL22631866 0.73 MEN1 (0.56)
SCHEMBL13924963 0.73 MEN1 (0.40)
SCHEMBL13924964 0.73 MEN1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0115811-B1 2,4-DICHLOR-5-THIAZOLECARBOXALDEHYD AND A PROCESS FOR ITS PREPARATION BAYER AG (DE) 1990-04-18 EP claimed
US-4910316-A Reacting 2,4-dichloro-5-thiazolecarboxaldehyde with thionyl chloride BAYER AKTIENGESELLSCHAFT (DE) 1990-03-20 US claimed
EP-0308740-A1 Process for the preparation of 2,4-dichloro-5-dichloromethyl thiazole BAYER AG (DE) 1989-03-29 EP claimed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US claimed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP claimed
EP-4746965-A1 BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4746964-A1 NEW PYRAZOLOPYRIDINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4727950-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2026-04-22 EP disclosed
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
EP-4578451-A2 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS Novartis AG (CH) 2025-07-02 EP disclosed
CN-119874654-A Pyran compound as plant immune activator and application thereof 华东理工大学 2025-04-25 CN disclosed
EP-4214210-B1 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS NOVARTIS AG (CH) 2025-04-09 EP disclosed
EP-0308740-A1 Process for the preparation of 2,4-dichloro-5-dichloromethyl thiazole BAYER AG (DE) 1989-03-29 EP disclosed
EP-0175610-A2 New cephalosporin compounds and the production thereof MEIJI SEIKA KAISHA LTD. (JP) 1986-03-26 EP disclosed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed
US-4555577-A 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP disclosed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP disclosed
EP-0115811-A2 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation BAYER AG (DE) 1984-08-15 EP disclosed