Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17782662 | 0.83 | KDM4E (0.53) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL20740108 | 0.79 | L3MBTL1 (0.54) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL30996440 | 0.79 | L3MBTL1 (0.54) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL30617194 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL7216296 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL9016652 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL11832759 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL13518625 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL20749427 | 0.76 | ALDH1A1 (0.36) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL1279441 | 0.72 | KDM4E (0.66) | SMN1; SMN2MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444253-A1 | PROCESS FOR PREPARING AD-35 | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2019-02-20 | — | — | EP | disclosed |