Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 17/20 | 0.38 |
| ▸ | DRD2 | P14416 | 18/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23125441 | 0.91 | DRD1 (0.40) | DRD1DRD2DRD4 | |
| SCHEMBL15047808 | 0.88 | DRD2 (0.39) | DRD1DRD2DRD4 | |
| SCHEMBL20751562 | 0.87 | DRD2 (0.38) | DRD1DRD2DRD4 | |
| SCHEMBL20751694 | 0.85 | DRD2 (0.36) | DRD1DRD2 | |
| SCHEMBL20751623 | 0.85 | DRD2 (0.36) | DRD1DRD2 | |
| SCHEMBL24199398 | 0.81 | DRD2 (0.40) | DRD1DRD2DRD4 | |
| SCHEMBL24199399 | 0.80 | DRD2 (0.41) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL23125443 | 0.79 | DRD2 (0.41) | DRD1DRD2DRD4 | |
| SCHEMBL15047809 | 0.79 | DRD2 (0.40) | DRD1DRD2DRD4 | |
| SCHEMBL20751555 | 0.78 | DRD2 (0.40) | DRD1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2790734-B1 | PRODRUGS OF SECONDARY AMINE COMPOUNDS | ALKERMES PHARMA IRELAND LTD (IE) | 2019-02-20 | — | — | EP | disclosed |