Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 16/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 2/20 | 0.60 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20752231 | 0.84 | IGF1R (0.51) | LRRK2JAK2BRD4IGF1R | |
| SCHEMBL20752307 | 0.84 | JAK2 (0.55) | JAK2BRD4IGF1R | |
| SCHEMBL20752074 | 0.83 | SYK (0.64) | JAK2IGF1R | |
| SCHEMBL20752134 | 0.81 | PRKCQ (0.58) | LRRK2JAK2BRD4 | |
| SCHEMBL20752222 | 0.81 | IGF1R (0.51) | LRRK2JAK2BRD4IGF1R | |
| SCHEMBL20752300 | 0.80 | SRC (0.56) | LRRK2IGF1R | |
| SCHEMBL20752169 | 0.80 | ULK1 (0.63) | LRRK2 | |
| SCHEMBL29575097 | 0.78 | BRD4 (0.72) | JAK2BRD4 | |
| SCHEMBL17544617 | 0.78 | BRD4 (0.72) | JAK2BRD4 | |
| SCHEMBL18739945 | 0.78 | BRD4 (0.54) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928891-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2019-02-20 | — | — | EP | disclosed |