SCHEMBL2075233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6300165	0.78	HTT (0.55)	ALDH1A1HTTTDP1LMNAMAPT
	SCHEMBL311004	0.76	ALDH1A1 (0.54)	ALDH1A1HTTTDP1LMNAMAPT
	SCHEMBL7345284	0.76	KCNJ1 (0.59)	ALDH1A1HTTTDP1MEN1PKM
	SCHEMBL6791413	0.75	HTT (0.51)	ALDH1A1HTTTDP1LMNAMAPT
	SCHEMBL9127112	0.74	HTT (0.61)	ALDH1A1HTTTDP1LMNAMAPT
	SCHEMBL3171647	0.74	KCNJ1 (0.58)	ALDH1A1HTTTDP1MEN1PKM
	SCHEMBL5388591	0.74	ALDH1A1 (0.54)	ALDH1A1HTTLMNAMEN1KMT2A
	SCHEMBL1929880	0.72	LTA4H (0.57)	ALDH1A1TDP1LMNAMAPTMEN1
	SCHEMBL264564	0.72	LTA4H (0.57)	ALDH1A1TDP1LMNAMAPTMEN1
	SCHEMBL7238168	0.72	HTT (0.62)	ALDH1A1HTTTDP1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.