SCHEMBL20753258

SCHEMBL20753258

COS(=O)(=O)CC[n+]1ccc(-c2ncccn2)cn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 2/20 0.33
CYP2A6 P11509 1/20 0.32
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22350853 0.92 CLK4 (0.32) CLK4CYP2A6DYRK1A
SCHEMBL24001022 0.91 CLK4 (0.31) CLK4
SCHEMBL24001058 0.88
SCHEMBL24001053 0.87 LMNA (0.33)
SCHEMBL24000927 0.87 CYP2A6 (0.37) CYP2A6
SCHEMBL24001057 0.87 APLNR (0.30)
SCHEMBL24001132 0.87 NPC1 (0.35)
SCHEMBL24001051 0.87 PDE4B (0.30)
SCHEMBL20753789 0.86 CLK4 (0.35) CLK4CYP2A6DYRK1A
SCHEMBL20753726 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3923724-B1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-26 EP disclosed
EP-3668855-B1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-11-10 EP disclosed
WO-2020164922-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164971-A1 PRE-HARVEST DESICCATION METHOD SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164924-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164920-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164923-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2019034757-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-02-21 WO disclosed