Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058111 | 1.00 | KDM4E (0.44) | KDM4EMAPK1ATMHSP90AA1ALOX15 | |
| SCHEMBL30969099 | 1.00 | KDM4E (0.44) | KDM4EMAPK1ATMHSP90AA1ALOX15 | |
| SCHEMBL30295894 | 0.82 | PKM (0.62) | KDM4EMAPK1ALOX15TDP1PKM | |
| SCHEMBL443524 | 0.80 | KDM4E (0.33) | KDM4EMAPK1ATMHSP90AA1PKM | |
| SCHEMBL20602047 | 0.80 | ALOX15 (0.33) | KDM4EMAPK1ATMHSP90AA1ALOX15 | |
| SCHEMBL8681096 | 0.80 | MAPK1 (0.43) | KDM4EMAPK1ATMHSP90AA1TSHR | |
| SCHEMBL444379 | 0.80 | KDM4E (0.33) | KDM4EMAPK1ATMHSP90AA1PKM | |
| SCHEMBL21552927 | 0.80 | KDM4E (0.34) | KDM4EMAPK1ATMHSP90AA1ALOX15 | |
| SCHEMBL8926462 | 0.80 | AHR (0.34) | KDM4EMAPK1ATMHSP90AA1ALOX15 | |
| SCHEMBL2362429 | 0.80 | AHR (0.37) | KDM4EMAPK1ATMHSP90AA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056663-A1 | EXPANSION POLYMERIZATION IMPRINTING GLUE FOR NANO-PRINTING | SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) | 2019-02-21 | — | — | US | disclosed |