Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30529587 | 0.89 | KDM4E (0.45) | DRD2DRD3PNMTSNCAIMPDH2 | |
| SCHEMBL21383855 | 0.89 | KDM4E (0.45) | DRD2DRD3PNMTSNCAIMPDH2 | |
| Hydrochloric Acid SCHEMBL15798908 | 0.83 | SNCA (0.38) | DRD2DRD3PNMTSNCAIMPDH2 | |
| SCHEMBL30294431 | 0.75 | PNMT (0.54) | DRD2DRD3PNMTIMPDH2IMPDH1 | |
| SCHEMBL4060436 | 0.75 | PNMT (0.54) | DRD2DRD3PNMTIMPDH2IMPDH1 | |
| SCHEMBL29242099 | 0.75 | SNCA (0.47) | DRD2DRD3PNMTSNCAIMPDH2 | |
| SCHEMBL6618447 | 0.74 | CYP11B1 (0.47) | SNCAMAOBKDM4EMAPTALDH1A1 | |
| SCHEMBL6615390 | 0.74 | GSK3B (0.44) | DRD2DRD3MAOBKDM4EMAPT | |
| SCHEMBL19848290 | 0.71 | IMPDH2 (0.39) | DRD2DRD3PNMTSNCAIMPDH2 | |
| SCHEMBL748146 | 0.71 | PNMT (0.55) | DRD2DRD3PNMTIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-110099898-A | compound and use thereof | 优曼尼蒂治疗公司 | 2019-08-06 | — | — | CN | disclosed |
| WO-2019036024-A1 | 2-(1,1 '-BIPHENYL)-1 H-BENZO[D]IMIDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS APELIN AND APJ AGONISTS FOR TREATING CARDIOVASCULAR DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-21 | — | — | WO | disclosed |
| CN-103998443-B | There is the cyclohexylamine derivant of the activity of beta 2-adrenergic agonist and M3 muscarine antagonist | 阿尔米雷尔有限公司 | 2016-08-24 | — | — | CN | disclosed |