Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024738 | 0.84 | CAPN1 (0.43) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL3866137 | 0.84 | ALDH1A1 (0.53) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL15957011 | 0.84 | CAPN1 (0.46) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL24024845 | 0.84 | CAPN1 (0.43) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL7510270 | 0.84 | ALDH1A1 (0.53) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL25267609 | 0.84 | CAPN1 (0.46) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL9542347 | 0.84 | ALDH1A1 (0.53) | MMP9PSMB1PSMB5PSMB2CAPN1 | |
| SCHEMBL23394724 | 0.83 | CAPN1 (0.42) | MMP3MMP9PSMB1PSMB5PSMB2 | |
| SCHEMBL5493308 | 0.82 | ALDH1A1 (0.55) | PSMB1PSMB5PSMB2CAPN1CTSK | |
| SCHEMBL5493312 | 0.82 | ALDH1A1 (0.55) | PSMB1PSMB5PSMB2CAPN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190054181-A1 | FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS | TRUSTEES OF TUFTS COLLEGE | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190054181-A1 | FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS | FAP, PSMA1, PSMA6 | MMP3 776/4885MMP9 1044/4885PSMB1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.