Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20757858 | 1.00 | HTR6 (0.48) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL18082909 | 0.91 | HTR6 (0.52) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL12534 | 0.91 | HTR6 (0.52) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL12533 | 0.91 | HTR6 (0.52) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL23588777 | 0.89 | HTR6 (0.42) | HTR6ARG1ARG2 | |
| SCHEMBL5228670 | 0.89 | HTR6 (0.57) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL27046822 | 0.89 | HTR6 (0.42) | HTR6ARG1ARG2 | |
| SCHEMBL23588776 | 0.89 | HTR6 (0.42) | HTR6ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL31015226 | 0.87 | HTR6 (0.55) | HTR6ARG1ARG2HTR3EHTR3B | |
| SCHEMBL24185129 | 0.85 | HTR6 (0.53) | HTR6HTR3EHTR3BHTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034890-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-02-21 | — | — | WO | disclosed |