Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 2/20 | 0.30 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23588777 | 1.00 | HTR6 (0.42) | HTR6CCNT1CDK9KHKARG1 | |
| SCHEMBL27046822 | 1.00 | HTR6 (0.42) | HTR6CCNT1CDK9KHKARG1 | |
| SCHEMBL20757858 | 0.89 | HTR6 (0.48) | HTR6ARG1ARG2 | |
| SCHEMBL23482908 | 0.89 | HTR6 (0.48) | HTR6 | |
| SCHEMBL20758015 | 0.89 | HTR6 (0.48) | HTR6ARG1ARG2 | |
| SCHEMBL23507346 | 0.88 | KDM4E (0.32) | — | |
| SCHEMBL5225386 | 0.88 | HTR6 (0.50) | HTR6KHK | |
| SCHEMBL23252499 | 0.88 | KDM4E (0.32) | — | |
| SCHEMBL23588772 | 0.85 | HTR6 (0.42) | HTR6ARG1ARG2 | |
| SCHEMBL23588773 | 0.85 | HTR6 (0.42) | HTR6ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129820-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | 微境生物医药科技(上海)有限公司 | 2021-07-01 | — | — | WO | disclosed |