Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7 | P36402 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758351 | 0.86 | CACNA1H (0.36) | CACNA1HAPPNAMPTMEN1KMT2A | |
| SCHEMBL22778947 | 0.81 | CACNA1H (0.40) | CACNA1HAPPNAMPTMEN1KMT2A | |
| SCHEMBL30341644 | 0.77 | CACNA1H (0.38) | CACNA1HAPPNAMPTMEN1KMT2A | |
| SCHEMBL20421239 | 0.74 | CACNA1H (0.48) | CACNA1HAPPNAMPTHDAC8SMN1; SMN2 | |
| SCHEMBL1618004 | 0.74 | APP (0.39) | CACNA1HAPPNAMPTMEN1KMT2A | |
| SCHEMBL8222771 | 0.73 | CTNNB1 (0.51) | CACNA1HCTNNB1TCF7 | |
| SCHEMBL22607388 | 0.73 | TP53 (0.34) | CACNA1HNAMPTHDAC8ABL1SMN1; SMN2 | |
| SCHEMBL21260285 | 0.73 | CACNA1H (0.33) | CACNA1HNAMPTHDAC8KDM4E | |
| SCHEMBL8253677 | 0.71 | MPO (0.44) | CACNA1HHDAC8ABL1CTNNB1TCF7 | |
| SCHEMBL7920028 | 0.71 | CCR1 (0.43) | CACNA1HAPPNAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | CHRM1, CHRM2, ACHE | CACNA1H 1195/4885APP 661/4885NAMPT 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.