Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18736529 | 0.94 | KMT2A (0.54) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL18736332 | 0.92 | TDP1 (0.54) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL22257619 | 0.90 | KMT2A (0.53) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL22498801 | 0.90 | PPARG (0.56) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL16897964 | 0.89 | KMT2A (0.73) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL18703863 | 0.88 | KMT2A (0.61) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL18705337 | 0.88 | PPARD (0.56) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL18736318 | 0.87 | NPC1 (0.52) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL20758458 | 0.86 | KMT2A (0.51) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL4500586 | 0.86 | KMT2A (0.67) | KMT2ATDP1SLC6A2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | KYOWA KIRIN CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| US-10745700-B2 | Nucleic acid conjugate | KYOWA KIRIN CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20190192674-A1 | NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-06-27 | — | — | US | disclosed |
| US-20190055558-A1 | NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | NSUN3, NSUN2, RNASEH1 | KMT2A 1750/4885TDP1 613/4885SLC6A2 1074/4885 |
| US-10745700-B2 | Nucleic acid conjugate | SLC29A1, NSUN2, H1-2 | KMT2A 871/4885TDP1 410/4885SLC6A2 883/4885 |
| US-20190192674-A1 | NUCLEIC ACID CONJUGATE | M6PR, NSUN2, NSUN3 | KMT2A 577/4885TDP1 2231/4885SLC6A2 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.