Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20759806 | 0.78 | HTR2C (0.40) | SIGMAR1HTR2CHTR6QDPRCCNT1 | |
| SCHEMBL29138608 | 0.76 | SIGMAR1 (0.55) | SIGMAR1HTR2CHTR6MAPTHTR1B | |
| SCHEMBL20759680 | 0.76 | BTK (0.36) | HTR2CHTR6HTR2AHTR7QDPR | |
| SCHEMBL28439457 | 0.75 | HTR6 (0.39) | HTR2CHTR6HTR2AHTR7CCNT1 | |
| SCHEMBL20759670 | 0.75 | HTR6 (0.39) | HTR2CHTR6HTR2AHTR7CCNT1 | |
| Hydrochloric Acid SCHEMBL31572375 | 0.75 | HTR2C (0.56) | SIGMAR1HTR2CHTR6MAPTHTR1B | |
| Hydrochloric Acid SCHEMBL28448600 | 0.75 | HTR2C (0.38) | HTR2CHTR6HTR2AHTR7CCNT1 | |
| Hydrochloric Acid SCHEMBL28448601 | 0.75 | HTR2C (0.38) | HTR2CHTR6HTR2AHTR7CCNT1 | |
| SCHEMBL24335744 | 0.72 | HTR2C (0.38) | SIGMAR1HTR2CHTR6HTR2AHTR7 | |
| Trifluoroacetic Acid SCHEMBL30863752 | 0.70 | HTR6 (0.38) | HTR2CHTR6HTR2AHTR7CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034128-A1 | PYRROLOTRIAZINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 | 2019-02-21 | — | — | WO | disclosed |