SCHEMBL20760804

SCHEMBL20760804

CC(C)=CCC/C(C)=C/CN(C/C=C/c1ccccc1)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.49
PPARA Q07869 7/20 0.49
TRPV1 Q8NER1 2/20 0.38
ICMT O60725 1/20 0.38
GMNN O75496 1/20 0.38
TRPA1 O75762 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
CDK2 P24941 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20780003 0.83 PPARG (0.52) PPARGPPARATRPV1ICMTGMNN
SCHEMBL19299692 0.83 PPARG (0.52) PPARGPPARATRPV1ICMTGMNN
SCHEMBL17685641 0.81 PPARG (0.58) PPARGPPARATRPV1ICMTGMNN
SCHEMBL17685642 0.81 PPARG (0.58) PPARGPPARATRPV1ICMTGMNN
SCHEMBL20759688 0.80 KDM4E (0.51) LMNACYP1A2TSHRHIF1AKDM4E
SCHEMBL20759689 0.80 KMT2A (0.56) CYP3A4MAPTKDM4EKMT2A
SCHEMBL23879508 0.80 PPARG (0.52) PPARGPPARATRPV1ICMTGMNN
SCHEMBL19301866 0.73 PPARG (0.53) PPARGPPARATRPV1ICMTGMNN
SCHEMBL8222914 0.72 KMT2A (0.50) PPARGPPARATRPV1ICMTGMNN
SCHEMBL31310902 0.71 PPARG (0.57) PPARGPPARATRPV1ICMTGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168466-A1 COATING COMPRISING ANTI-MICROBIAL PARTICLES, METHODS OF PREPARATION AND USES THEREOF NOBIO LTD. (IL) 2022-06-02 US disclosed
US-20220142155-A1 ANTI-MICROBIAL PARTICLES AND METHODS OF USE THEREOF NOBIO LTD. (IL) 2022-05-12 US disclosed
US-11178867-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups NOBIO LTD. (IL) 2021-11-23 US disclosed
US-20190053487-A1 MICRO AND NANOPARTICULATE COMPOSITIONS COMPRISING ANTI-MICROBIALLY ACTIVE GROUPS NOBIO LTD. (IL) 2019-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142155-A1 ANTI-MICROBIAL PARTICLES AND METHODS OF USE THEREOF LPO, MPO, CAPG PPARG 2893/4885PPARA 1053/4885TRPV1 3282/4885
US-11178867-B2 Micro and nanoparticulate compositions comprising anti-microbially active groups MPO, LPO, DSTN PPARG 2603/4885PPARA 1915/4885TRPV1 3170/4885
US-20220168466-A1 COATING COMPRISING ANTI-MICROBIAL PARTICLES, METHODS OF PREPARATION AND USES THEREOF CAPG, MPO, LPO PPARG 2619/4885PPARA 1429/4885TRPV1 4302/4885
US-20190053487-A1 MICRO AND NANOPARTICULATE COMPOSITIONS COMPRISING ANTI-MICROBIALLY ACTIVE GROUPS MPO, LPO, DSTN PPARG 2603/4885PPARA 1915/4885TRPV1 3170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.