Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852987 | 0.88 | NLRP3 (0.63) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL19272297 | 0.82 | NLRP3 (0.54) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL20634490 | 0.81 | NLRP3 (0.56) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL19272199 | 0.81 | NLRP3 (0.60) | NLRP3ALDH1A1 | |
| SCHEMBL22251833 | 0.79 | NLRP3 (0.54) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL21646639 | 0.79 | NLRP3 (0.54) | NLRP3ALDH1A1 | |
| SCHEMBL25848429 | 0.79 | NLRP3 (0.54) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL20713466 | 0.79 | NLRP3 (0.54) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL19801726 | 0.77 | NLRP3 (0.56) | NLRP3ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL6866811 | 0.77 | NLRP3 (0.57) | NLRP3ALDH1A1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034696-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |