SCHEMBL30852987

SCHEMBL30852987

O=C(Nc1c2c(cc3c1CCC3)CCC2)Nc1c2c(cc3c1CCC3)CCC2

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 17/20 0.63
ALDH1A1 P00352 1/20 0.60
ATM Q13315 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19272199 0.88 NLRP3 (0.60) NLRP3ALDH1A1
SCHEMBL20760949 0.88 NLRP3 (0.56) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL20634490 0.88 NLRP3 (0.56) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL21646639 0.85 NLRP3 (0.54) NLRP3ALDH1A1
SCHEMBL19272297 0.85 NLRP3 (0.54) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL25848429 0.85 NLRP3 (0.54) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL20713466 0.85 NLRP3 (0.54) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL19801726 0.84 NLRP3 (0.56) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL18029669 0.83 NLRP3 (0.53) NLRP3ALDH1A1ATMSMN1; SMN2
SCHEMBL6866811 0.83 NLRP3 (0.57) NLRP3ALDH1A1ATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024057249-A1 IMPROVED PROCESS FOR THE PREPARATION OF SULFONYLUREA BASED COMPOUNDS ZYDUS LIFESCIENCES LIMITED (IN) 2024-03-21 WO disclosed