Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565864 | 0.85 | KDM4E (0.61) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL3287137 | 0.85 | KDM4E (0.61) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL2076150 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL30607591 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL30748716 | 0.83 | KDM4E (0.59) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL3290416 | 0.83 | KDM4E (0.59) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL6822065 | 0.83 | KDM4E (0.59) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL2750963 | 0.82 | KDM4E (0.58) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL27939424 | 0.82 | KDM4E (0.58) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL5901321 | 0.82 | KDM4E (0.68) | ALDH1A1MAPTDRD2HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | claimed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | claimed |
| CN-101052620-A | Benzamide compound | ASTRAZENECA AB (SE) | 2007-10-10 | — | — | CN | claimed |
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | disclosed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
| CN-101052620-A | Benzamide compound | ASTRAZENECA AB (SE) | 2007-10-10 | — | — | CN | disclosed |
| WO-2006024841-A2 | BENZAMIDE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293687-A1 | Benzamide Compounds | HDAC1, HDAC11, HDAC2 | ALDH1A1 299/4885MAPT 2809/4885DRD2 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.