Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.48 |
| ▸ | RXRG | P48443 | 9/20 | 0.48 |
| ▸ | RXRB | P28702 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20763235 | 0.98 | TSHR (0.45) | RXRARXRGRXRBTSHRALDH1A1 | |
| SCHEMBL20763298 | 0.90 | RXRA (0.45) | RXRARXRGRXRBNAAATHRB | |
| SCHEMBL20763289 | 0.87 | RXRA (0.43) | RXRARXRGRXRBTSHRALDH1A1 | |
| SCHEMBL13506252 | 0.86 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL21242530 | 0.86 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL21242234 | 0.86 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL20763309 | 0.85 | PSEN1 (0.41) | RXRARXRGRXRBTSHRALDH1A1 | |
| SCHEMBL20763291 | 0.85 | PSEN1 (0.41) | RXRARXRGRXRBTSHRALDH1A1 | |
| SCHEMBL20762847 | 0.85 | THRB (0.40) | RXRARXRGRXRBTSHRALDH1A1 | |
| SCHEMBL21242266 | 0.85 | TSHR (0.59) | TSHRALDH1A1CYP3A4THRBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |