Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973095 | 0.83 | EPHX2 (0.34) | EPHX2ALDH1A1 | |
| SCHEMBL25973097 | 0.79 | HDAC1 (0.38) | EPHX2ALDH1A1CNR1MAPTSMN1; SMN2 | |
| SCHEMBL20651093 | 0.79 | HDAC1 (0.38) | EPHX2ALDH1A1CNR1MAPTSMN1; SMN2 | |
| SCHEMBL27316261 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CNR1CNR2TSHRMAPK1 | |
| SCHEMBL27309028 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CNR1CNR2TSHRMAPK1 | |
| SCHEMBL19203662 | 0.75 | PAOX (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL16847680 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1TSHRMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL16847589 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1TSHRMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19265338 | 0.73 | HDAC1 (0.37) | EPHX2ALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL18105555 | 0.72 | PTGS1 (0.50) | ALDH1A1CNR1CNR2FAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019033773-A1 | TETRAMALEIMIDE LINKERS AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2019-02-21 | — | — | WO | disclosed |