SCHEMBL207641

SCHEMBL207641

c1ccc(On2cccn2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
GLA P06280 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 2/20 0.35
LTA4H P09960 1/20 0.35
TBXAS1 P24557 1/20 0.33
MAPK1 P28482 2/20 0.32
CA4 P22748 1/20 0.32
KCNN4 O15554 1/20 0.32
KCNA3 P22001 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NOTUM Q6P988 1/20 0.31
CYP19A1 P11511 3/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4723132 0.83
SCHEMBL4729215 0.77 CYP19A1 (0.42) TSHRTBXAS1CYP19A1
SCHEMBL8178619 0.75 MAPT (0.46) GLARAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL10474636 0.75 LMNA (0.42) RAB9AALDH1A1MAPTHTTNPSR1
SCHEMBL1817016 0.74 KDM4E (0.38) NPC1GLARAB9ASMN1; SMN2LTA4H
SCHEMBL10876324 0.72 CYP19A1 (0.41) GLATSHRLTA4HTBXAS1CA4
SCHEMBL9595941 0.72 MAPK1 (0.38) MAPK1ALDH1A1MAPTHTTNPSR1
SCHEMBL27848866 0.72 MEN1 (0.40) NPC1GLARAB9ASMN1; SMN2TSHR
SCHEMBL17714126 0.71 LTA4H (0.32) TSHRLTA4HCA4
SCHEMBL99339 0.69 TSHR (0.41) TSHRLTA4HALDH1A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970651-A Pyrazole phenyl ethers methoxy acrylate derivative and its preparation method and application 南开大学 2019-07-05 CN claimed
EP-1074551-B1 Phenylpyrazoles with a herbicidal activity ISAGRO RICERCA SRL (IT) 2003-03-26 EP claimed
US-5256626-A Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds MONSANTO COMPANY (US) 1993-10-26 US claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
US-20250185657-A1 PEST CONTROLLING AGENT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-06-12 US disclosed
EP-4501924-A1 PEST CONTROLLING AGENT Nippon Kayaku Kabushiki Kaisha (JP) 2025-02-05 EP disclosed
WO-2023190286-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2023-10-05 WO disclosed
WO-2022259985-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2022-12-15 WO disclosed
CN-113980117-A Fenpyroximate antigen and preparation method and application thereof 西南大学 2022-01-28 CN disclosed
CN-108029692-B Compound composition containing sulfur fluorine oxime ether and application thereof 湖南化工研究院有限公司 2020-11-20 CN disclosed
WO-2020054712-A1 PEST CONTROL AGENT 日本化薬株式会社 2020-03-19 WO disclosed
US-4948902-A Process for making substituted pyrazoles MONSANTO COMPANY (US) 1990-08-14 US disclosed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP disclosed
EP-0370990-A1 Herbicidal substituted pyrazoles MONSANTO COMPANY (US) 1990-05-30 EP disclosed
EP-0354201-A2 Safening herbicidal benzoic acid derivatives MONSANTO COMPANY (US) 1990-02-07 EP disclosed
US-4855442-A Substituted 3-hydroxy pyrazoles MONSANTO COMPANY (US) 1989-08-08 US disclosed
US-4855442-A Substituted 3-hydroxy pyrazoles MONSANTO COMPANY (US) 1989-08-08 US disclosed
CN-1033457-A 3-(4-nitrophenoxy) pyrazoles that replaces and as the purposes of weedicide MONSANTO CO (US) 1989-06-21 CN disclosed
EP-0304409-A1 5-Heterocyclic-substituted oxazolidine haloacetamides MONSANTO COMPANY (US) 1989-02-22 EP disclosed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250185657-A1 PEST CONTROLLING AGENT CBR1, CBR3, CYC1 NPC1 1359/4885GLA 4634/4885RAB9A 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.