SCHEMBL20764313

SCHEMBL20764313

Nc1ccc2nc(C(=O)Oc3c(F)c(F)c(F)c(F)c3F)sc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
ALDH1A1 P00352 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
LMNA P02545 1/20 0.48
KEAP1 Q14145 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
HPGD P15428 2/20 0.46
SHMT2 P34897 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 1/20 0.46
APP P05067 1/20 0.44
RAB9A P51151 3/20 0.41
GAA P10253 3/20 0.41
NPC1 O15118 2/20 0.41
KDM4E B2RXH2 2/20 0.41
GLA P06280 2/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4936252 0.82 ALDH1A1 (0.63) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL20764179 0.78 MAPT (0.64) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL1621400 0.77 SMN1; SMN2 (0.46) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL20764173 0.76 CYP2C9 (0.55) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL30916109 0.75 CA1 (0.57) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL3080605 0.75 CA1 (0.57) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL30916141 0.73 MAPT (0.53) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL25219141 0.71 MAPT (0.64) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL30040343 0.71 MAPT (0.64) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL28664679 0.69 SMN1; SMN2 (0.50) MAPTALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019036225-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2019-02-21 WO disclosed