Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717232 | 0.84 | HTT (0.54) | CA1CA2CA4GAAAPP | |
| SCHEMBL27281190 | 0.84 | MAPT (0.51) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL3709201 | 0.83 | RAB9A (0.51) | MAPTALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL5028769 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL28930490 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2CA2MAPTALDH1A1MEN1 | |
| SCHEMBL23249736 | 0.80 | GAA (0.47) | SMN1; SMN2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL3943416 | 0.79 | MAPT (0.47) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL6632291 | 0.79 | CYP1A2 (0.54) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL29248357 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2CA1CA2MAPTALDH1A1 | |
| SCHEMBL28588889 | 0.77 | NPC1 (0.60) | SMN1; SMN2CA1CA2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594671-B | Benzothiazole derivative, preparation method and application thereof | 沈阳药科大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-113831301-B | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115594671-A | Benzothiazole derivative and preparation method and application thereof | 沈阳药科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115515944-A | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-113831301-A | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2021-12-24 | — | — | CN | disclosed |