Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | NGFR | P08138 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764301 | 0.90 | KIF11 (0.37) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20764163 | 0.88 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20764181 | 0.86 | HRH4 (0.50) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20764300 | 0.86 | BTK (0.34) | RAB9AHRH4NGFRPOLBKDM4E | |
| SCHEMBL20764325 | 0.79 | MAPT (0.37) | NPC1RAB9APOLBMAPTLMNA | |
| SCHEMBL889826 | 0.76 | KMT2A (0.40) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20764411 | 0.75 | BTK (0.35) | RAB9AHRH4POLBMAPTKDM4E | |
| SCHEMBL20764330 | 0.74 | BTK (0.34) | POLBLMNAKIF11BAZ2B | |
| SCHEMBL20764323 | 0.73 | HRH4 (0.46) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL13183210 | 0.73 | RAB9A (0.41) | NPC1RAB9AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036225-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2019-02-21 | — | — | WO | disclosed |