Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRPR | P30550 | 8/20 | 0.56 |
| ▸ | NMBR | P28336 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 3/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312760 | 0.90 | GRPR (0.69) | GRPRNMBRCTSLCTSSCTSK | |
| SCHEMBL23273234 | 0.89 | GRPR (0.55) | GRPRKEAP1GLP1R | |
| SCHEMBL30628980 | 0.87 | GRPR (0.64) | GRPRNMBR | |
| SCHEMBL31738529 | 0.87 | GRPR (0.62) | GRPRNMBRCTSLCTSSCTSK | |
| SCHEMBL31223171 | 0.86 | GRPR (0.57) | GRPRNMBRKEAP1C5AR1 | |
| SCHEMBL38660949 | 0.86 | GRPR (0.57) | GRPRNMBRKEAP1C5AR1 | |
| SCHEMBL30415473 | 0.85 | CTSL (0.54) | CTSLCTSSCTSKCTSHC5AR1 | |
| SCHEMBL30883276 | 0.85 | CTSL (0.61) | CTSLCTSSCTSKCTSHGLP1R | |
| SCHEMBL30628976 | 0.85 | GRPR (0.59) | GRPRNMBR | |
| SCHEMBL31026128 | 0.85 | GHSR (0.54) | CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672626-A1 | COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS | Onkologix Ltd (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038671-A1 | COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS | ONKOLOGIX LTD (US) | 2019-02-28 | — | — | WO | disclosed |