Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764591 | 0.85 | NPC1 (0.43) | ADRB2ADRB1ADRB3EP300MAPT | |
| SCHEMBL20764555 | 0.75 | SMN1; SMN2 (0.44) | ADRB2ADRB1ADRB3MAPTNPC1 | |
| SCHEMBL26259401 | 0.74 | EP300 (0.50) | ADRB2ADRB1ADRB3EP300ALDH1A1 | |
| SCHEMBL24211477 | 0.72 | EP300 (0.67) | EP300MAPTNPC1RAB9ATSHR | |
| SCHEMBL20786869 | 0.71 | SMN1; SMN2 (0.41) | ADRB2ADRB1ADRB3MAPTNPC1 | |
| SCHEMBL28372325 | 0.71 | SMN1; SMN2 (0.36) | ADRB2ADRB1ADRB3EP300MAPT | |
| SCHEMBL20764510 | 0.71 | SMN1; SMN2 (0.48) | ADRB2ADRB1ADRB3EP300MAPT | |
| SCHEMBL31311198 | 0.68 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL20787606 | 0.68 | SMN1; SMN2 (0.43) | ADRB2ADRB1ADRB3MAPTNPC1 | |
| SCHEMBL20764572 | 0.68 | ALDH1A1 (0.51) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672937-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |