Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764591 | 0.86 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20764510 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20787606 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20764555 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20786864 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20787426 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20764535 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL28372325 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20786866 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL20764597 | 0.71 | ADRB2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |