Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787 | 1.00 | MEN1 (0.34) | MEN1KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL29397787 | 0.88 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1610399 | 0.86 | MEN1 (0.37) | MEN1KMT2ATDP1ALDH1A1SLC6A3 | |
| SCHEMBL29399995 | 0.85 | CA1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4633132 | 0.84 | MEN1 (0.34) | MEN1KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL29870181 | 0.84 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL29870007 | 0.83 | NAAA (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10704941 | 0.83 | NAAA (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL29397857 | 0.82 | EPHX1 (0.33) | MEN1KMT2ASLC6A3EPHX1 | |
| SCHEMBL8078214 | 0.80 | MAPT (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |