Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.47 |
| ▸ | LPL | P06858 | 7/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892633 | 0.78 | LPL (0.32) | LIPGLPL | |
| SCHEMBL15441588 | 0.76 | LPL (0.36) | LIPGLPL | |
| SCHEMBL6225264 | 0.76 | LIPG (0.51) | LIPGLPLHSD17B1HSD17B2NPC1 | |
| SCHEMBL16373588 | 0.74 | LPL (0.32) | LIPGLPL | |
| SCHEMBL25896361 | 0.72 | LIPG (0.47) | LIPGLPLMAPTNPC1MEN1 | |
| SCHEMBL1758541 | 0.71 | LPL (0.46) | LIPGLPLMAPTNPC1KMT2A | |
| SCHEMBL26109871 | 0.71 | LIPG (0.46) | LIPGLPLMAPTANPEPLAP3 | |
| SCHEMBL20079509 | 0.70 | LIPG (0.41) | LIPGLPLANPEPLAP3 | |
| SCHEMBL20983994 | 0.69 | LIPG (0.63) | LIPGLPLHSD17B1HSD17B2ESR1 | |
| SCHEMBL22299971 | 0.69 | LIPG (0.47) | LIPGLPLHSD17B1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |