⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475572 | 0.73 | — | — | |
| SCHEMBL20207458 | 0.70 | — | — | |
| SCHEMBL12360630 | 0.70 | — | — | |
| SCHEMBL20207347 | 0.70 | — | — | |
| SCHEMBL562401 | 0.70 | — | — | |
| SCHEMBL23126862 | 0.69 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4655483 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8752911 | 0.69 | ODC1 (0.33) | — | |
| SCHEMBL17474716 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL65860 | 0.68 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672978-A1 | PROCESS FOR MAKING IXAZOMIB OR INTERMEDIATES THEREFOR | Synthon B.V. (NL) | 2020-07-01 | — | — | EP | claimed |
| WO-2019038406-A1 | PROCESS FOR MAKING IXAZOMIB OR INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2019-02-28 | — | — | WO | claimed |
| EP-3672978-A1 | PROCESS FOR MAKING IXAZOMIB OR INTERMEDIATES THEREFOR | Synthon B.V. (NL) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038406-A1 | PROCESS FOR MAKING IXAZOMIB OR INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2019-02-28 | — | — | WO | disclosed |